Levofloxacin can cause serious side effects, including tendon problems, side effects on your nerves (which may cause permanent nerve damage), serious mood or behavior changes (after just one dose), or low blood sugar (which can lead to coma). PURPOSE. Azithromycin use has been associated with increased risk of death among patients at high baseline risk, but not for younger and middle-aged adults. Can you take azithromyacin. Can you take azithromyacin and levofloxacin together- my doctor gave me both ? Asked 2 Sep 2011 by patjune Updated 2 September 2011 Topics levofloxacin, doctor. Answer this question. Responses (1) SU. suzanne66 3 Sep 2011. More than one type of antibiotic is often prescribed for nasty bacterial infections. The antibiotics you have been prescribed are effective. You can take levofloxacin before or after meals. If you are taking one dose a day, it is preferable to take it in the morning. If you are taking more than one dose a day, try to space out your doses - so ideally, take a tablet every 12 hours. Areas covered. Case reports/case series, observational studies and clinical trials assessing cardiovascular risks associated with azithromycin and levofloxacin were critically reviewed, including 15 case reports/series, 5 observational studies and 5 clinical trials that investigated the cardiac risks associated azithromycin and levofloxacin. azithromycin oral and levofloxacin oral both increase QTc interval. Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational Compare Azithromycin vs. Levofloxacin, which is better for uses like: Infection, Chlamydia and UTI. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Azithromycin 3.3/5 over Levofloxacin 2.6/5 in overall satisfaction. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Gallant on levaquin and azithromycin: You can, but you should have a good reason, and they should be prescribed by a health care provider. Can't take Levaquin (levofloxacin) at the same time as antacids or vitamins. Levaquin (levofloxacin) can increase your skin's sensitivity to sunlight and make you more likely to get a rash. Relatively more expensive compared to similar alternatives.